法人別リリース Tue, 19 Nov 2024 16:00:bcゲーム 出金速度 hourly 1 bcゲーム 出金速度ita to Launch Injectable-grade Pharmaceutical Excipient "SUCROSE SG" in 2025 /release/202411119717 Tue, 19 Nov 2024 16:00:bcゲーム 出金速度 bcゲーム 出金速度ita bcゲーム 出金速度ita Co., Ltd., a member of the NAGASE Group headquartered in Okayama Japan, is set to expan... bcゲーム 出金速度ita Co., Ltd.
bcゲーム 出金速度ita Co., Ltd., a member of the NAGASE Group headquartered in Okayama Japan, is set to expand the line of SOLBIOTE (TM), saccharide-based pharmaceutical excipients, with the launch of high-purity and low-endotoxin SUCROSE SG by June 2025. The portfolio of SOLBIOTE (TM) includes TREHALOSE SG and MALTOSE PH, which are the signature products of pharmaceutical ingredients, and with the addition of SUCROSE SG to the portfolio, it offers a comprehensive range of solutions for stability in biopharmaceutical development.

Image1:https://cdn.kyodonewsprwire.jp/prwfile/release/M104815/202411119717/bcゲーム 出金速度rwbcゲーム 出金速度I1fl_4X4BN8eY.jpg

Sucrose is widely used as a stabilizer in biopharmaceuticals, a rapidly growing market. It helps maintabcゲーム 出金速度he quality of antibody drugs and lipid nanoparticles (LNPs) formulated with nucleic acid, such as COVID-19 vaccines.

Since its founding, sustainability and biotechnology have been at the core of bcゲーム 出金速度ita’s business. SUCROSE SG is produced in an environmentally friendly way by using water instead of solvents.

Image2:https://cdn.kyodonewsprwire.jp/prwfile/release/M104815/202411119717/bcゲーム 出金速度rwbcゲーム 出金速度I2fl_4w2ywc0c.jpg

The name SOLBIOTE (TM) is derived from "Sol + Bio," representing biotechnology and the sun's gift of starch ("Sol" meaning "sun" in Latin). bcゲーム 出金速度ita’s excipients are designed to provide innovative solutions for biopharmaceuticals, offering a stable supply and guaranteeing exceptional quality.

Find out more about SOLBIOTE (TM):
https://group.nagase.com/viita/en/highlights/solbiote/
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bcゲーム 出金速度ita Launches SOLBIOTE (TM), New Brand of Injectable-grade Saccharide Excipients ... /release/202406031668 Mon, 10 Jun 2024 16:00:bcゲーム 出金速度 bcゲーム 出金速度ita bcゲーム 出金速度ita Co., Ltd., a member of the NAGASE Group headquartered in Okayama Japan, has launched a... bcゲーム 出金速度ita Co., Ltd.
bcゲーム 出金速度ita Co., Ltd., a member of the NAGASE Group headquartered in Okayama Japan, has launched a new product brand, SOLBIOTE (TM), featuring its saccharide-based pharmaceutical excipients of high-purity and low-endotoxin TREHALOSE SG and MALTOSE PH.

SOLBIOTE (TM) portfolio is an excellent protein stabilizer, protecting cells, nucleotides, and exosomes from various damage caused by stressors such as drying, freezing, bcゲーム 出金速度hawing. It preserves the quality of antibody therapeutics, vaccines, and other biopharmaceuticals, which are inherently unstable during manufacturing, storage, and distribution, requiring adequate cold-chain management.

Image1: SOLBIOTE (TM) portfolio; bcゲーム 出金速度G and MALTOSE PHhttps://cdn.kyodonewsprwire.jp/prwfile/release/M104815/202406031668/bcゲーム 出金速度rwbcゲーム 出金速度I1fl_MyQw9rBz.jpg

bcゲーム 出金速度ita has a long history of harnessing the power of nature and an expertise in biotechnology, which led it to be the first to successfully mass produce trehalose utilizing starch and enzymes. It is committed to providing a stable supply of safe, high-quality excipients through its integrated manufacturing from saccharide production to refining.

bcゲーム 出金速度ompany will further pursue the development of new saccharide excipients for the SOLBIOTE (TM) portfolio and its advanced pharmaceutical applications, bringing pharmaceutical solutions for universal health.

Image2: Image of SOLBIOTE (TM)https://cdn.kyodonewsprwire.jp/prwfile/release/M104815/202406031668/bcゲーム 出金速度rwbcゲーム 出金速度I2fl_hrz1tewp.jpg

The name SOLBIOTE (TM) comes from "Sol + Bio," developed by bcゲーム 出金速度ompany's Biotechnology and starch, a gift from the sun (Sol meaning the sun in Latin), providing Solutions to Biopharmaceuticals.

bcゲーム 出金速度urther details, visit:https://group.nagase.com/viita/en/products_solutions/pharmaceutical_ingredients/
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bcゲーム 出金速度ita Receives Highest "Platinum" Rating for Sustainability from EcoVadis /release/202403298779 Wed, 03 Apr 2024 15:00:bcゲーム 出金速度 bcゲーム 出金速度ita bcゲーム 出金速度ita Co., Ltd., a NAGASE Group member headquartered in Okayama, Japan, has received the hig... bcゲーム 出金速度ita Co., Ltd.
bcゲーム 出金速度ita Co., Ltd., a NAGASE Group member headquartered in Okayama, Japan, has received the highest "Platinum" rating in a sustainability survey conducted by EcoVadis SAS of France, one of the world's most trusted providers of business sustainability ratings for global supply chains. The "Platinum" rating is awarded to companies that score in the top 1% of all eligible companies.

Image:
https://cdn.kyodonewsprwire.jp/prwfile/release/M104815/202403298779/bcゲーム 出金速度rwbcゲーム 出金速度I1fl_H72Ovpu6.png

EcoVadis assesses suppliers operating in 180+ countries across 220+ industries, and assessment results are tested on over 130,000 companies. EcoVadis conducts objective examinations and assessments of companies' sustainability through independent reviews and analyses, scoring the performance on a company's policies, actions and results, in four sustainability themes: Environment, Labor & Human Rights, Ethics, and Sustainable Procurement. bcゲーム 出金速度ita received a Gold rating in 2022 and a Silver rating in 2023.

In this latest examination, the company increased its scores in the areas of environmental policy and implementation measures, labor and human rights policy, and sustainable procurement policy, actions, and results. In addition, bcゲーム 出金速度ita was also recognized for its "use of eco-friendly or bio-based input materials," the assessment results of which led to its "Platinum" rating this time around.

bcゲーム 出金速度ita is committed to the wider aim of contributing to the SDGs (Sustainable Development Goals) to realize a sustainable society through its business activities. Encouraged by this Platinum rating, bcゲーム 出金速度ita will continue to promote measures to resolve social issues, improve its corporate value and continue to be sought after by its stakeholders.

Comments:/attach/202403298779-O1-4j15545J.pdf

About bcゲーム 出金速度ita Co., Ltd.:

Originally established in 1883, bcゲーム 出金速度ita Co., Ltd. (formerly Hayashibara Co., Ltd.) began its journey as a syrup manufacturer. Over the years, it has evolved into a pioneer in harnessing the potential of nature, specializing in products utilizing microorganisms and enzymes. Today, its portfolio spans a diverse array of functional materials, catering to industries ranging from food, personal care, and pharmaceuticals to industrial and agricultural sectors.

On April 1, 2024, the company was officially rebranded as bcゲーム 出金速度ita. The new name embodies the collaborative synergy among NAGASE Group entities, dedicated to delivering innovative products and value propositions on a global scale.

bcゲーム 出金速度urther details, visit:https://group.nagase.com/viita/en/

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Seeding Future: Hayashibara’s 25th Trehalose Symposium Highlightbcゲーム 出金速度reakthroughs /release/202311142769 Fri, 17 Nov 2023 16:00:bcゲーム 出金速度 bcゲーム 出金速度ita Hayashibara Co., Ltd., a bcゲーム 出金速度f Nagase Group and headquartered in Okayama City, western Japan, s... Hayashibara Co., Ltd.
Hayashibara Co., Ltd., a member of Nagase Group and headquartered in Okayama City, western Japan, successfully conducted the "25th Trehalose Symposium," an annual interdisciplinary event since 1997, on November 2, 2023, bcゲーム 出金速度okyo.

Photos:https://cdn.kyodonewsprwire.jp/prwfile/release/M104815/202311142769/bcゲーム 出金速度rwbcゲーム 出金速度I1fl_m5nZa589.jpg

Under the theme of "Trehalose Leading a Sustainable Future," bcゲーム 出金速度ymposium featured various research outcomes.These included promising treatments using three-dimensional cultures and dermal sheets from fibroblastbcゲーム 出金速度rocessed with highly concentrated trehalose, the design of stem cell preservation solutions, and the applications in hair care products and livestock feed. bcゲーム 出金速度hemistry and biological functions of trehalose-based compounds were also presented. Particularly noteworthy was Dr. Benedetto Marelli's presentation, "Trehalose-based Seed Coating to Boost Agriculture in Marginal Lands." Dr. Marelli, an Associate Professor of Civil and Environmental Engineering at the Massachusetts Institute of Technology (MIT), highlighted how the formulation, incorporating trehalose and silk protein, leads to innovation in enhancing sustainable agriculture and food systems. The presented study confirmed that this seed-coating technology significantly improves seed germination, even in lands traditionally unsuitable for farming due to high-stress conditions. This breakthrough not only addresses bcゲーム 出金速度hallenges brought on by climate change but also showcases trehalose's role in increasing crop yields, enhancing quality, and promoting the development of a beneficial rhizosphere.

The company will transition its name from "Hayashibara" to "bcゲーム 出金速度ita" in April 2024, marking the 140th year since its establishment. This rebranding reflects its unwavering commitment to building a sustainable society and dedication to continuing the tradition of hosting this symposium into the future.

Symposium details:https://www.hayashibara.co.jp/data/6957/bcゲーム 出金速度symposium_tp/

Past presentations:https://www.hayashibara.co.jp/data/6753/bcゲーム 出金速度rd_tp/

About the bcゲーム 出金速度ymposium
Founded in 1997, the Trehalose Symposium habcゲーム 出金速度een promoting research and development activities for trehalose while assisting researchers in publicizing their discoveries. For the last 25 years, 193 researchers with multi-disciplinary scientific backgrounds have presented the properties of trehalose and its functionalities.

bcゲーム 出金速度rehalose
Trehalose is a naturally occurring disaccharide long known for its biochemical effect on protecting cells and tissues under dry conditions. Studies have revealed that trehalose’s physicochemical properties, such as water binding and vitrification, are behind the protective functionality. The development of applied research empowered the food, pharmaceutical, and cosmetic industries to utilize trehalose bcゲーム 出金速度heir commercial products.

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Hayashibara Bringbcゲーム 出金速度ack "Trehalose Symposium" to Reveal Its Game-changing Versatilities ... /release/202209297422 Tue, 04 Oct 2022 15:00:bcゲーム 出金速度 bcゲーム 出金速度ita Hayashibara Co., Ltd., a bcゲーム 出金速度f Nagase Group and headquartered in Okayama City, western Japan, h... Hayashibara Co., Ltd.
Hayashibara Co., Ltd., a member of Nagase Group and headquartered in Okayama City, western Japan, hosted the 24th Trehalose Symposium, with bcゲーム 出金速度upport of the Japanese Society of Applied Glycoscience, on September 8, 2022.

Photo:/prwfile/release/M104815/202209297422/bcゲーム 出金速度rwbcゲーム 出金速度I1fl_JX2ftzQv.png

This highly specialized academic event returned to Tokyo after a three-year hiatus, engaging 231 attendees in person and online from various fields. Researchers from home and abroad presented their basic and applied research results on trehalose. The presentations included the development of a vaccine stabilization method that holds promise for transport without the need for a cold chain, basic research on how trehalose affects ice crystal growth to identify improved thawing techniques for cryopreserved biological tissues, and research on the application of trehalose to surgical treatment, utilizing autophagy (recycling function within cells), featured bcゲーム 出金速度he 2016 Nobel Prizes.

During a discussion session, followed by the presentations, Japanese experts shared their viewpoints on why and how most organisms utilize trehalose over other carbohydrates. At the end of bcゲーム 出金速度ession, bcゲーム 出金速度peakers addressed their prospects and expectations for future research and development while indicating the importance of basic research.

Hayashibara is dedicated to continuing the Trehalose Symposium, providing a community for researchers worldwide to present their findings and obtain beneficial information by interacting with peers. Through its commitment to basic research for trehalose, Hayashibara envisions the Trehalose Symposium to contribute to building bcゲーム 出金速度ustainable society.

For details of bcゲーム 出金速度ymposium, visit:https://www.hayashibara.co.jp/data/6801/bcゲーム 出金速度symposium_tp/

For bcゲーム 出金速度ast 187 presentations, visit:https://www.hayashibara.co.jp/data/6753/bcゲーム 出金速度rd_tp/

About the bcゲーム 出金速度ymposium
Founded in 1997, the Trehalose Symposium habcゲーム 出金速度een promoting research and development activities for trehalose while assisting researchers in publicizing their discoveries. For the last 20 years, 187 researchers with multi-disciplinary scientific backgrounds have presented the properties of trehalose and its functionalities.

bcゲーム 出金速度rehalose
Trehalose, found in food items like mushrooms, is a naturally occurring disaccharide long known for its biochemical effect on protecting cells and tissues under dry conditions. Studies have revealed that trehalose’s physicochemical properties, such as water binding and vitrification, are behind the protective functionality. The development of applied research empowered the food, pharmaceutical, and cosmetic industries to utilize trehalose bcゲーム 出金速度heir commercial products.

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Hayashibara, Member of NAGASE Group, Offerbcゲーム 出金速度otential Solutions to Cutting Down on Waste ... /release/201912134759 Mon, 16 Dec 2019 14:00:bcゲーム 出金速度 bcゲーム 出金速度ita Hayashibara Co., Ltd. of Okayama, bcゲーム 出金速度ubsidiary of NAGASE & Co., Ltd., held a workshop on Nov. 18-20 ... Hayashibara, Member of NAGASE Group, Offerbcゲーム 出金速度otential Solutions to Cutting Down on Waste in Foodservice Industries in North America
Hayashibara Co., Ltd. of Okayama, a subsidiary of NAGASE & Co., Ltd., held a workshop on Nov. 18-20 at bcゲーム 出金速度ulinary Institute of America (CIA) at Copia, in Napa, California, USA as the Nagase Food Ingredients. Twelve prominent North American chefs, who are experts in foodservice and R&D, came together to appreciate global cuisines and learn new skills and techniques to enhance their foodservice operations.

The workshop showcased many applications of TREHA (R) (trehalose), a plant-based food ingredient with bcゲーム 出金速度mazing natural functionalities of extending freshness of foods (examples are shown below). TREHA is derived from starch and is GRAS-designated, Non-GMO, and Kosher- and Halal-certified.

Application details:/prwfile/release/M104815/201912134759/bcゲーム 出金速度rwbcゲーム 出金速度A1fl_8eI2GXkr.pdf

Two guest chefs demonstrated several applications in Japanese dishes--sushi, tempura bcゲーム 出金速度ofu--as well as Western confectionaries, cheesecake and matcha creme brulee. They shared their experience and advice, including benefits in reducing food waste, operation costs, and maintaining freshness and outstanding food quality for their consumers.

After learning TREHA’s unique functionalities, each of the chefs had applied their new knowledge to creating their own recipe. bcゲーム 出金速度hree days, more than 25 different dishes were presented on the table and created exciting discussion about the effectiveness and use of TREHA.

Furthermore, in respect to contributions towards two of the UN SDGs--(2) Zero Hunger and (12) Responsible Consumption and Production--, bcゲーム 出金速度ttending chefs learned about how using novel food ingredients can have enormous impact in sustainability on a North American and global scale.

In large-scale foodservice operations, where enormous amounts of food are prepared (banquets, catering for inflight and cruises), it is challenging to maintain high quality of freshness--especially on buffet lines and in mass production where food may be held prior to serving. bcゲーム 出金速度hefs were very excited to learn how TREHA can be applied to preserve freshness longer in both fresh and frozen food applications.

The workshop gave potential solutions to global food issues by utilizing TREHA’s unique functionalities such as extending bcゲーム 出金速度helf life of foods, keeping freshness longer, especially fresh vegetables and fruits, and improving quality in a variety of foods.

The moderator, Chef Barbara Alexander, the former CIA executive chef, was fascinated to see that a salad prepared the day before was as fresh and crisp after more than 12 hours. This demonstrated TREHA’s natural ability to prevent vegetables from going limp and preserving bcゲーム 出金速度runchy texture for a longer period of time. In addition, one of bcゲーム 出金速度hefs tried TREHA on roast chicken, and the attending chefs were amazed at the difference in juiciness and the beautiful golden colored skin.

Please visit:
https://www.nagase-foods.com/treha/

*bcゲーム 出金速度nterview with Chef Barbara Alexander
YouTube:https://www.youtube.com/watch?v=Vj7bOZPXM0U


From bcゲーム 出金速度ducational perspective, Nagase Food Ingredients is committed to providing useful information to the global foodservice industries.

Official website:https://www.hayashibara.co.jp/data/en/


Source: Hayashibara Co., Ltd.
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Hayashibara Assessment of “Nature” Article, bcゲーム 出金速度tatement on Safety of TREHA(R) (trehalose) /release/201802090834 Tue, 13 Feb 2018 15:00:bcゲーム 出金速度 bcゲーム 出金速度ita In regards to bcゲーム 出金速度cently published article "Dietary trehalose enhances virulence of epidemic Clost... Hayashibara Co., Ltd.
Hayashibara Assessment of “Nature” Article, bcゲーム 出金速度tatement on Safety of TREHA(R) (trehalose)
In regards to the recently published article "Dietary trehalose enhances virulence of epidemic Clostridium difficile" bcゲーム 出金速度he journal Nature, Hayashibara Co., Ltd. would like to share its assessment of web-based comments, news and blogs, and make a statement on the safety of its product, TREHA(R) (trehalose), as a manufacturer of trehalose.

1. Relationship between the regulatory status of trehalose bcゲーム 出金速度nd outside Japan, and the epidemic outbreaks of Clostridium difficile (CD)
TREHA(R) (trehalose) was launched in 1995 bcゲーム 出金速度he Japanese market and then introduced outside Japan. Since then, TREHA(R) (trehalose) has been used in Japan in a wide variety of foods by many customers for over 20 years. The Nature article discusses that the virulent epidemics are concurrent with the regulatory status of trehalose “approvals” bcゲーム 出金速度he United States (GRAS in 2000) and Europe (Novel Food in 2001); however, no epidemics of any kind were noted in Japan bcゲーム 出金速度he 5 years previous to the “approvals” of trehalose bcゲーム 出金速度he United States and Europe.

According to the diagram bcゲーム 出金速度he article, there was a virulent CD epidemic outbreak in Canada around 2003. However, TREHA(R) (trehalose) was not available bcゲーム 出金速度he market or used in any food items in Canada until its approval in mid-June 2005. In addition, the regulatory status of trehalose did not allow for its import or use in several of the other countries described bcゲーム 出金速度he article such as Kuwait, Costa Rica, Iran and Panama, where epidemic outbreaks were confirmed.

Based on Hayashibara’s estimate of the intake of trehalose from natural foods and ingredients in a normal diet bcゲーム 出金速度he United States, the intake of Hayashibara’s trehalose would be minimal, less than 5% of the naturally occurring trehalose in general food items. This is unlikely to justify the concurrence of the epidemic outbreaks.

Considering these facts, Hayashibara believes the presence of TREHA(R) (trehalose) bcゲーム 出金速度he food industries of the described counties does not support the conclusion of the correlation that is cited bcゲーム 出金速度he article.

2. Test results bcゲーム 出金速度nimals
The study employed a specific test system that challenged mice with the virulent strains after treating them with 6 types of antibiotics to sterilize their intestinal bacteria. Because the C57BL/6 mice have trehalase, an enzyme that breaks down trehalose bcゲーム 出金速度heir small intestines, it is highly likely that the trehalose given to the mice broke down into glucose and was subsequently absorbed as glucose bcゲーム 出金速度he small intestine. This process is identical to that of oral administration of glucose or other disaccharides. Another dispute is that the study does not show comparative results with other carbohydrates containing glucose as a carbon source.

3. bcゲーム 出金速度f trehalose on intestinal bacteria
In humans and other mammals, trehalose is hydrolyzed to glucose by trehalase, which is located bcゲーム 出金速度he small intestine. The glucose is subsequently absorbed bcゲーム 出金速度he small intestine as glucose, as explained above. It is Hayashibara’s contention that the amount of trehalose in an intact form reaching the large intestine is too small to initiate any significant effects on intestinal bacteria.

A human oral clinical test conducted at the University of Colorado confirmed that consumption of 100g/day of trehalose for 12 weekbcゲーム 出金速度y subjects with an average age of 64 years resulted in no severe side effects, including bowel inflammation (Aging (2016) 8, 1167–1183).

Press Release in Korean
https://www.hayashibara.co.jp/press/kr1.html
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