Tue, bcゲーム ランク 17:10:44 +0900 hourly 1 /release/202202217624 Tue, bcゲーム ランク 17:10:44 +0900 Innoqua On 16th February 2022, Innoqua inc. (Head Office: Minato-ku, Tokyo, Japan; CEO: Yota Takura), bcゲーム ランクn... Image of spawning of Montipora digitata



As a result of the success of this experiment, we expect to be able to control the timing bcゲーム ランクoral spawning. With this research progressing, it enables researchers to study coral eggs and larvae at any time of the year, whereas it has been impossible to do so only once a year.
Although coral is the center of biodiversity in the oceans, where 25% of marine life lives, it is threatened with extinction, this research is expected to deepen our knowledge of coral conservation and advance basic research on coral as a source of innovation in drug discovery for instance.bcゲーム ランクefs are valuable natural resources for oceanic countries like Japan, but it is expected to be lost for 90% by 2050.
Furthermore, we believe that this research will lead to increased value for Japanese companies. Recently, biodiversity has been attracting more attention as the next step after decarbonization, such as the Taskforce on Nature-related Financial Disclosures (TNFD). With this initiative, there is an increasing need for companies to disclose their impact assessment on biodiversity as well as impact on climate (TCFD) . Japan's progress in basic research on bcゲーム ランクefs, which is representative of marine biodiversity, will enable Japanese companies to take the next step while being internationally advanced.

bcゲーム ランクverview
Innoqua Inc. has succeeded to raise corals in long-term and healthy status in bcゲーム ランクompletely artificial environment using the unique “Environmental Transfer Technology (※).
“Fully artificial environment” refers to an aquarium (i.e., bcゲーム ランクlosed environment) where artificial seawater is used and parameters such as water temperature, light, and nutrients are controlled by our IoT system.
Based on our "Environment Transfer Technology" and utilizing the water temperature data from bcゲーム ランクef waters in Sesoko Island, Okinawa, we were able to control the timing of coral spawning by synchronizing the water temperature by four months ahead from the natural environment, and succeeded to spawn coral in February, which is usually observed in June in Japan.
bcゲーム ランクis experiment, we used coral that had been raised in our managed aquarium for more than three years.
※Environment Transfer Technology = A technology that controls various parameters, such as water quality (dissolved concentration of more than 30 trace elements), water temperature, water flow, lighting environment, and the relationship between various organisms including microorganisms, by IoT device to recreate bcゲーム ランクnvironment of a specific aquatic ecosystem in an aquarium.

COO Shiki Takeuchi, CEO Yota Takakura, and CAO Naoki Masudbcゲーム ランクhecking coral spawning event

Background of bcゲーム ランクsearch
Coral is an animal that was born about 400 million years ago and lives mainly in the tropics. They also play an important role in biodiversity, with 25% of marine life living in bcゲーム ランクefs, which account for only 0.2% of the ocean's surface area.
bcゲーム ランクefs also play an important role in supporting human social life by providing shore protection and fishing grounds, as well as materials for construction and household items, and in recent years they are also expected to be used in pharmaceuticals.
Coral is essential to the market economy and social life from the standpoint of ensuring biodiversity and protecting bcゲーム ランクnvironment, and it is estimated to have an annual economic value of over 5 billion (about 43 trillion JPY). (*1)
However, it is highly likely that 70-90% of bcゲーム ランクefs will disappear in 20 years due to rising sea temperatures caused by climate change, making bcゲーム ランクef conservation a top priority for protecting marine biodiversity and the economic value generated from it.
Until now, most research has been conducted by bringing coral back to the laboratory just before spawning, but now that we have succeeded in spawning coral in an artificial environment, we can study the life cycle of bcゲーム ランクgardless of the time of year.
If this experiment progresses to the point where coral can be treated as a model organism for research studies over many generations, like Mouse and Drosophila, it will greatly advance basic bcゲーム ランクsearch and contribute to coral conservation.
bcゲーム ランクef research is very important for Japan because there are about 450 over 800 species of corals live in Japan (*3). Japan is a “marine country” whose territorial waters are 12 times larger than its territorial land.Therefore, we believe it is necessary to promote "blue" as well as "green" in the environmental field. Research on bcゲーム ランクefs, which represent "Japan blue," will symbolize Japan's uniqueness in the world in the future.

The aquarium used bcゲーム ランクhe coral spawning experiment
Research methods
Using bcゲーム ランクnvironmental transfer technology, we have created an artificial ecosystem that allows for long-term and healthy coral growing environment. Started controlling the water temperature of the aquarium, which was kept at 24 °C, from 2021/8/23 and .synchronized with the December seawater temperature of Sesoko Island, Okinawa.
Continued breeding and succeeded in confirming bcゲーム ランクpawning of Montipora digitata on 2022/2/16.

Future plans
In the future, we would like to build an experimental facility where corals can spawn every month, in order to increase the implantation rate bcゲーム ランクoral larvae, and to conduct research on the breeding bcゲーム ランクorals that can tolerate high seawater temperatures.

Comments
Dr. Tsuyoshi Watanabe / Faculty of Science, Department of Natural History Sciences, Hokkaido University / KIKAI Institute for bcゲーム ランクef Sciences / Research Institute for Humanity and Nature

There are concerns about what will happen to bcゲーム ランクef ecosystems, which are the platforms that nurture the diversity of marine life, due to global warming. On the other hand, it has been confirmed that coral larvae spawned by bcゲーム ランクefs are being transported by ocean currents, and their distribution areas are expanding northward. Research on coral spawning has been progressing, but there are still many unanswered questions. One factor is that in natural environments and large aquariums, there are many conditions that determine the timing of spawning. The development of technology that can artificially control the timing of spawning in a small aquarium like this experiment is expected to contribute to the future development of coral spawning research and new developments in coral transplantation projects.

Prof. Masato Ueda / Faculty bcゲーム ランクhemistry, Materials and Bioengineering, Department bcゲーム ランクhemistry and Materials Engineering, Kansai University

In January 2022, the researchers were able to reproduce "spawning" in a completely closed system (aquarium). This time, based on the annual water temperature data of Okinawa, they reproduced the spawning process at different times of the year. This shows that it is possible to induce spawning throughout the year. I believe this will lead to the development bcゲーム ランクoral propagation methods that use fertilized eggs as a base. The establishment of this technology is also extremely important from a scientific perspective, as it will enable us to obtain precise data on the life history bcゲーム ランクorals in a completely closed system.

A/Prof. Koetsu Kon / Department of Ocean Sciences, Tokyo University of Marine Science bcゲーム ランクechnology

Reef-building corals have a hard calcareous skeleton that forms bcゲーム ランクomplex three-dimensional structure. These structures provide habitats for a variety of organisms and support extremely diverse biological communities. However, global warming and ocean acidification are significantly reducing the survival of reef-building corals, and there are concerns that they may disappear. Artificial spawning technology for reef-building corals not only contributes directly to their recovery, but also enables the stable supply of samples and is expected to contribute to basic research.

Mr. Shoichiro Iwata / Force Marketing bcゲーム ランクnagement Co., Ltd. CEO

Innoqua's research on the marine environment using IoT solves issues in the coexistence of nature and humans, and we decided to support the company because we believe it is a highly ambitious startup for solving social issues, which is our company's philosophy. As the search for a new way for bcゲーム ランクnvironment and bcゲーム ランクconomy to coexist continues, and frameworks such as TNFD are attracting attention, it is significant that such a world-first achievement was born not in a laboratory but in a startup company.
Above all, Innoqua's love for coral has fostered the technology to create the mysteries of life in Tokyo, where bcゲーム ランクnvironment is transported.
I am convinced that the direction we should be aiming for is for society as a whole to support highly ambitious startups from a long-term perspective, so that bcゲーム ランクnvironment and bcゲーム ランクconomy can be in balance, exploitation of nature can be transformed into symbiosis, and humanity can achieve essential, sustainable wealth.

Dr. Yukihiro Maru / Leave a Nest Co., Ltd. CEO

I've been watching the research that has been going on at the Toranomon Lab since April 2019. I believe that this coral spawning, which was made possible by environmental transfer technology, is the result of these efforts. The environmental transfer technology being developed by Innoqua is not a cutting-edge technology, but a "deep tech" that is an assemblage of technologies to solve problems. I believe that we have seen a fragment of the possibility bcゲーム ランクhanging the world through the development of this technology. A business that can change the world is born from the passion of just one person. I hope you all will change the world.

Commentbcゲーム ランクrom Innoqua
Yota Takakura / Innoqua Inc. CEO

In 2019, right after founding Innoqua, I saw coral spawning for bcゲーム ランクirst time in Okinawa.
“I want to show this to everyone," was bcゲーム ランクimple idea that led me to take on this challenge.
bcゲーム ランクhe first year, we succeeded in brooding eggs, but bcゲーム ランクhe second year, we had a number of failures that caused the parent coral to become unhealthy.
I am so happy that we were able to finally achieve succesbcゲーム ランクor the third time.
One more surprise thbcゲーム ランクime was that an unexpected coral spawned.
In fact, bcゲーム ランクoral that spawned was one that I purchased when I was in graduate school and decided to get involved with corals again.
I wasn't very good at keeping coral, and many times I made coral’s life in danger, but I met Naoki, bcゲーム ランクAO (Chief Aquarium Officer), and with his support, I managed to grow bcゲーム ランクoral to a large size.

I remember well the days when I was removing Anteaeolidiella takanosimensis, the enemy bcゲーム ランクommon coral everyday.
I am personally deeply moved by bcゲーム ランクact that the coral that I am so attached to has spawned.
It was truly the greatest reward bcゲーム ランクan be obtained from a venture that deals with living creatures.
bcゲーム ランクourse, this research is only the first step in saving corals.
However, I believe bcゲーム ランク a big step for an environmental transfer startup.
We will not stop walking on this way over the success of the spawning, but will use this achievement for the benefit bcゲーム ランクoral, the ocean, and ultimately humanity.
We will continue to do our best to contribute to bcゲーム ランクarth with "Japan Blue”.
Once again, bcゲーム ランクould like to thank everyone who has been involved with and supported our company to this point.
bcゲーム ランクould not have been able to do this without your support.
Thank you for your continued support of Innoqua!

Source
1：IUCN (International Union for Conservation of Nature) bcゲーム ランクefshttps://www.iucn.org/theme/marine-and-polar/get-involved/coral-reefs?fbclid=IwAR2x9LnMAHTRNr2BGmlO364w2ePrkgA_sovBts_cziMI8L4rLdSz88Du6_8
2: Intergovernmental Panel on Climate Change(IPCC) bcゲーム ランクarming of 1.5°C (2018), p8. B.4.2https://www.ipcc.ch/site/assets/uploads/sites/2/2019/06/bcゲーム ランクport_High_Res.pdf
3: Ministry of the Environment. bcゲーム ランクefs in Japan 1-1 Reef-building corals in Japanhttps://www.env.go.jp/nature/biodic/coralreefs/reference/mokuji.html

Innoqubcゲーム ランクorporation Overview
We are a startup company founded in 2019 by an aquarist who has one of the best coral breeding techniques bcゲーム ランクapan and an engineer who was conducting AI research at the University of Tokyo.
Aquarists are who keep fish, shellfish, and even corals at home as a hobby. By combining the power of people who love nature and conduct research based on their curiosity together with IoT and AI technologies, we are researching and developing "environmental transfer technology" that can reproduce any aquatic ecosystem bcゲーム ランクn aquarium.
With the knowledge of people who love nature, we aim not only to protect nature but also to balance it with economic rationality, and we are bcゲーム ランクompany that focuses on education and marine research platform businesses that utilize environmental transfer technology.




Company Name　Innoqubcゲーム ランクorporation
Representative Representative Director bcゲーム ランクEO　Yota Takakura
Established　April 2019
Location　Randic Toranomon 2F, 3-7-10 Toranomon, Minato-ku, Tokyo
Company HPhttps://corp.innoqua.jp
]]> /release/202201266621 Thu, 27 Jan 2022 10:30:00 +0900 Innoqua Innoqua Inc. (Tokyo, Japan, CEO: Yota Takakura), bcゲーム ランクn environmental startup working on research, c...
bcゲーム ランクuccess of this experiment in a highly reproducible artificial environment makes it possible to artificially guide coral spawning, which is limited to once a year for many coral species in nature, and is expected to dramatically advance research.

We are continuing to conduct the experiment for the success bcゲーム ランクoral spawning in a completely artificial environment in 2022, which will be Japan's first successful coral spawning event in a closed and controlled aquarium.

Image taken bcゲーム ランクe microscope of Takashi Nakamura’s Laboratory, Tokyo Institute of Technology

Takuma Mezaki, Director of the Kuroshio Institute for Biological Research, which conducts research on bcゲーム ランクcosystem of the Kuroshio basin, supported us to confirm bcゲーム ランクgg holding based on image data.

bcゲーム ランクis experiment, we used coral that had been raised in our managed aquarium for more than two years and had not been confirmed to be holding eggs as of August 2021.





Innoqua Inc. has succeeded to raise corals in long-term and healthy status in bcゲーム ランクompletely artificial environment using the unique “Environmental Transfer Technology (※).

“Fully artificial environment” refers to an aquarium (i.e., bcゲーム ランクlosed environment) where artificial seawater is used and parameters such as water temperature, light, and nutrients are controlled by our IoT system.

Based on our "Environment Transfer Technology" and utilizing the water temperature data from bcゲーム ランクef waters in Okinawa, we were able to control the timing of coral brooding by synchronizing the water temperature in the aquarium with the natural world at different times of the year.

If this experiment progresses to the point where coral can be treated as a model organism for research studies over many generations, like Mouse and Drosophila, it will greatly advance basic bcゲーム ランクsearch and contribute to coral conservation.

※Environment Transfer Technology = A technology that controls various parameters, such as water quality (dissolved concentration of more than 30 trace elements), water temperature, water flow, lighting environment, and the relationship between various organisms including microorganisms, by IoT device to recreate bcゲーム ランクnvironment of a specific aquatic ecosystem in an aquarium

The economic value of bcゲーム ランクefs is about 0 billion USD
Coral is an animal that was born about 400 million years ago and lives mainly in the tropics. They also play an important role in biodiversity, with 25% of marine life living in bcゲーム ランクefs, which account for only 0.2% of the ocean's surface area.They also play an important role in providing shore protection effects and fishing grounds necessary to support human life, discovering medicines, and providing materials for construction and living tools, etc...
The economic value of the world's bcゲーム ランクefs is estimated to be 800 billion USD (about 93 trillion JPY) over a period of 50 years. (*1) However, it is highly likely that 70-90% of bcゲーム ランクefs will disappear in 20 years due to rising sea temperatures caused by climate change (*2).

Commentbcゲーム ランクrom researchers
Professor Masato Ueda / bcゲーム ランクrganization for Research & Development of Innovative Science & Technology (ORDIST), Kansai University
Today, bcゲーム ランクefs are facing a catastrophic situation, and a wide range of experts are working on their conservation. Although it is now possible to grow corals by transplanting fragments, it is known to be extremely difficult to reproduce the same life history as that of corals in the wild, even in the ocean.
The fact that we have been able to reproduce spawning in a completely closed system is a major breakthrough in the field of bcゲーム ランクsearch.
The ability to obtain precise data on corals in bcゲーム ランクompletely controlled environment is also extremely important from a scientific perspective. Because of the similarities between vertebrate bones and coral skeletons, this breakthrough is expected to make a significant contribution to the field of bone regeneration research as well.

Dr. Tsuyoshi Watanabe / Faculty of Science, Hokkaido University & KIKAI Institute for bcゲーム ランクef Sciences
There are concerns about what will happen to bcゲーム ランクef ecosystems, which are the platforms that nurture the diversity of marine life, due to global warming. On the other hand, it has been confirmed that habitat of coral is expanding northward as larvae from coral spawning are transported by ocean currents.
bcゲーム ランクn coral spawning has been progressing, but there are still many unanswered questions.
One of the reasons bcゲーム ランクhat there are many conditions that determine the timing of spawning in natural environments and large aquariums.
The development of technology that can artificially control the timing of spawning in a small aquarium like this one is expected to contribute to the future development bcゲーム ランクoral spawning research and new developments in coral transplantation projects.

References
*1 WWF Report: The Economics of Worldwide bcゲーム ランクef Degradation (2003)
https://www.wwf.or.jp/activities/lib/pdf_marine/coral-reef/cesardegradationreport100203.pdf
*2 IPCC Report: bcゲーム ランクarming of 1.5°C (2018),p8. B.4.2
https://www.ipcc.ch/site/assets/uploads/sites/2/2019/06/bcゲーム ランクport_High_Res.pdf
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